In the table below you can see the SeRenDIP PPI interface prediction example P0DTC5 — Name: SARS-CoV-2 Membrane protein — UniProtKB: VME1_SARS2
. The table
contains sequence position, prediction scores and classification based on the default cut-off of 0.5 (above is predicted interaction).
Qingzhen Hou1, Reza Haydarlou, Bas Stringer, Katharina Waury, Henriette Capel, Sanne Abeln, Jaap Heringa, K. Anton Feenstra
SeRenDIP-CE: Sequence-based Interface Prediction for Conformational Epitopes
Bioinformatics advance 11 May 2021, doi: 10.1093/bioinformatics/btab3211Department of Biostatistics, School of Public Health &
National institute of health data science of China; Shandong 250002, P. R. China
Qingzhen Hou1, Paul De Geest, Christian Griffioen, Sanne Abeln,
Jaap Heringa, K. Anton Feenstra.
SeRenDIP: remastered alignment profiles for fast
and accurate predictions of PPI interface positions.Bioinformatics 35, pp 4794–4796, 2019, doi: 10.1093/bioinformatics/btz428 13BIO-BioInfo – BioModeling, BioInformatics & BioProcesses, Université Libre de Bruxelles
Qingzhen Hou, Paul De Geest, Wim F. Vranken, Jaap Heringa and K. Anton Feenstra Seeing the Trees through the Forest:
Sequence-based Homo- and Heteromeric
Protein-protein Interaction sites prediction using
Random Forest. Bioinformatics, 2017, doi: 10.1093/bioinformatics/btx005
Color better than threshold:
Sequence
Combined Prediction
Pos
AA
Model
Pred
x of 214 rows match filter(s)
5
N
0.518
I
6
G
0.502
I
7
T
0.492
NI
8
I
0.476
NI
9
T
0.520
I
10
V
0.516
I
11
E
0.378
NI
12
E
0.456
NI
13
L
0.456
NI
14
K
0.442
NI
15
K
0.440
NI
16
L
0.446
NI
17
L
0.418
NI
18
E
0.498
NI
19
Q
0.476
NI
20
W
0.500
NI
21
N
0.518
I
22
L
0.476
NI
23
V
0.456
NI
24
I
0.480
NI
25
G
0.432
NI
26
F
0.398
NI
27
L
0.384
NI
28
F
0.392
NI
29
L
0.418
NI
30
T
0.372
NI
31
W
0.370
NI
32
I
0.352
NI
33
C
0.394
NI
34
L
0.372
NI
35
L
0.424
NI
36
Q
0.454
NI
37
F
0.476
NI
38
A
0.518
I
39
Y
0.472
NI
40
A
0.500
NI
41
N
0.512
I
42
R
0.496
NI
43
N
0.464
NI
44
R
0.476
NI
45
F
0.474
NI
46
L
0.392
NI
47
Y
0.384
NI
48
I
0.336
NI
49
I
0.348
NI
50
K
0.348
NI
51
L
0.352
NI
52
I
0.392
NI
53
F
0.366
NI
54
L
0.348
NI
55
W
0.368
NI
56
L
0.372
NI
57
L
0.394
NI
58
W
0.358
NI
59
P
0.378
NI
60
V
0.378
NI
61
T
0.348
NI
62
L
0.344
NI
63
A
0.314
NI
64
C
0.330
NI
65
F
0.358
NI
66
V
0.340
NI
67
L
0.354
NI
68
A
0.440
NI
69
A
0.482
NI
70
V
0.492
NI
71
Y
0.494
NI
72
R
0.524
I
73
I
0.484
NI
74
N
0.472
NI
75
W
0.486
NI
76
I
0.454
NI
77
T
0.466
NI
78
G
0.412
NI
79
G
0.408
NI
80
I
0.346
NI
81
A
0.328
NI
82
I
0.310
NI
83
A
0.310
NI
84
M
0.306
NI
85
A
0.302
NI
86
C
0.300
NI
87
L
0.352
NI
88
V
0.348
NI
89
G
0.354
NI
90
L
0.368
NI
91
M
0.360
NI
92
W
0.332
NI
93
L
0.352
NI
94
S
0.354
NI
95
Y
0.388
NI
96
F
0.364
NI
97
I
0.460
NI
98
A
0.446
NI
99
S
0.480
NI
100
F
0.488
NI
101
R
0.534
I
102
L
0.450
NI
103
F
0.454
NI
104
A
0.554
I
105
R
0.520
I
106
T
0.550
I
107
R
0.588
I
108
S
0.612
I
109
M
0.614
I
110
W
0.604
I
111
S
0.574
I
112
F
0.550
I
113
N
0.604
I
114
P
0.558
I
115
E
0.582
I
116
T
0.534
I
117
N
0.528
I
118
I
0.424
NI
119
L
0.370
NI
120
L
0.346
NI
121
N
0.368
NI
122
V
0.270
NI
123
P
0.488
NI
124
L
0.498
NI
125
H
0.484
NI
126
G
0.444
NI
127
T
0.416
NI
128
I
0.430
NI
129
L
0.426
NI
130
T
0.430
NI
131
R
0.430
NI
132
P
0.522
I
133
L
0.506
I
134
L
0.522
I
135
E
0.464
NI
136
S
0.460
NI
137
E
0.514
I
138
L
0.514
I
139
V
0.486
NI
140
I
0.458
NI
141
G
0.460
NI
142
A
0.470
NI
143
V
0.498
NI
144
I
0.470
NI
145
L
0.516
I
146
R
0.494
NI
147
G
0.466
NI
148
H
0.500
NI
149
L
0.368
NI
150
R
0.406
NI
151
I
0.410
NI
152
A
0.474
NI
153
G
0.478
NI
154
H
0.480
NI
155
H
0.472
NI
156
L
0.392
NI
157
G
0.412
NI
158
R
0.386
NI
159
C
0.406
NI
160
D
0.360
NI
161
I
0.376
NI
162
K
0.362
NI
163
D
0.348
NI
164
L
0.358
NI
165
P
0.362
NI
166
K
0.424
NI
167
E
0.394
NI
168
I
0.438
NI
169
T
0.354
NI
170
V
0.314
NI
171
A
0.324
NI
172
T
0.474
NI
173
S
0.496
NI
174
R
0.512
I
175
T
0.496
NI
176
L
0.462
NI
177
S
0.488
NI
178
Y
0.480
NI
179
Y
0.500
NI
180
K
0.564
I
181
L
0.486
NI
182
G
0.476
NI
183
A
0.458
NI
184
S
0.402
NI
185
Q
0.440
NI
186
R
0.382
NI
187
V
0.330
NI
188
A
0.364
NI
189
G
0.346
NI
190
D
0.370
NI
191
S
0.372
NI
192
G
0.374
NI
193
F
0.368
NI
194
A
0.316
NI
195
A
0.376
NI
196
Y
0.396
NI
197
S
0.460
NI
198
R
0.416
NI
199
Y
0.490
NI
200
R
0.490
NI
201
I
0.514
I
202
G
0.496
NI
203
N
0.454
NI
204
Y
0.526
I
205
K
0.518
I
206
L
0.510
I
207
N
0.568
I
208
T
0.596
I
209
D
0.584
I
210
H
0.624
I
211
S
0.594
I
212
S
0.570
I
213
S
0.520
I
214
S
0.504
I
215
D
0.518
I
216
N
0.510
I
217
I
0.508
I
218
A
0.554
I
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