In the table below you can see the SeRenDIP-CE Conformational Epitope prediction example P0DTC4 — Name: SARS-CoV-2 Envelope small membrane protein — UniProtKB: VEMP_SARS2
. The table
contains sequence position, prediction scores and classification based on the default cut-off of 0.5 (above is predicted interaction).
Qingzhen Hou1, Reza Haydarlou, Bas Stringer, Katharina Waury, Henriette Capel, Sanne Abeln, Jaap Heringa, K. Anton Feenstra
SeRenDIP-CE: Sequence-based Interface Prediction for Conformational Epitopes
Bioinformatics advance 11 May 2021, doi: 10.1093/bioinformatics/btab3211Department of Biostatistics, School of Public Health &
National institute of health data science of China; Shandong 250002, P. R. China
Qingzhen Hou1, Paul De Geest, Christian Griffioen, Sanne Abeln,
Jaap Heringa, K. Anton Feenstra.
SeRenDIP: remastered alignment profiles for fast
and accurate predictions of PPI interface positions.Bioinformatics 35, pp 4794–4796, 2019, doi: 10.1093/bioinformatics/btz428 13BIO-BioInfo – BioModeling, BioInformatics & BioProcesses, Université Libre de Bruxelles
Qingzhen Hou, Paul De Geest, Wim F. Vranken, Jaap Heringa and K. Anton Feenstra Seeing the Trees through the Forest:
Sequence-based Homo- and Heteromeric
Protein-protein Interaction sites prediction using
Random Forest. Bioinformatics, 2017, doi: 10.1093/bioinformatics/btx005
Color better than threshold:
Sequence
Models
Epitope Prediction
Pos
AA
Model 1
Model 2
Model 3
Model 4
Model 5
Average
Pred
Std. Dev.
Z-score
x of 67 rows match filter(s)
5
V
0.722
0.616
0.636
0.690
0.664
0.666
I
0.0422
1.7047
6
S
0.706
0.678
0.660
0.686
0.638
0.674
I
0.0259
1.8069
7
E
0.688
0.776
0.682
0.728
0.694
0.714
I
0.0392
2.3179
8
E
0.672
0.720
0.686
0.704
0.686
0.694
I
0.0186
2.0624
9
T
0.588
0.660
0.606
0.706
0.634
0.639
I
0.0465
1.3624
10
G
0.548
0.580
0.556
0.628
0.614
0.585
I
0.0351
0.6777
11
T
0.586
0.654
0.562
0.626
0.656
0.617
I
0.0417
1.0814
12
L
0.586
0.626
0.590
0.634
0.626
0.612
I
0.0226
1.0252
13
I
0.504
0.586
0.534
0.540
0.594
0.552
I
0.0377
0.2485
14
V
0.432
0.558
0.494
0.556
0.560
0.520
I
0.0565
-0.1552
15
N
0.450
0.576
0.460
0.528
0.622
0.527
I
0.0739
-0.0632
16
S
0.374
0.504
0.424
0.454
0.580
0.467
NI
0.0787
-0.8297
17
V
0.410
0.516
0.450
0.468
0.544
0.478
NI
0.0532
-0.6968
18
L
0.446
0.522
0.474
0.514
0.540
0.499
NI
0.0383
-0.4209
19
L
0.422
0.500
0.454
0.494
0.488
0.472
NI
0.0330
-0.7735
20
F
0.386
0.470
0.438
0.436
0.470
0.440
NI
0.0344
-1.1771
21
L
0.408
0.460
0.464
0.468
0.440
0.448
NI
0.0248
-1.0750
22
A
0.394
0.438
0.474
0.520
0.448
0.455
NI
0.0465
-0.9881
23
F
0.392
0.460
0.452
0.504
0.460
0.454
NI
0.0401
-1.0034
24
V
0.416
0.470
0.462
0.530
0.454
0.466
NI
0.0411
-0.8399
25
V
0.400
0.474
0.448
0.496
0.436
0.451
NI
0.0367
-1.0392
26
F
0.364
0.478
0.432
0.486
0.430
0.438
NI
0.0487
-1.2027
27
L
0.356
0.498
0.384
0.442
0.424
0.421
NI
0.0547
-1.4224
28
L
0.340
0.490
0.390
0.406
0.458
0.417
NI
0.0587
-1.4735
29
V
0.328
0.500
0.374
0.372
0.462
0.407
NI
0.0711
-1.5961
30
T
0.330
0.462
0.368
0.410
0.456
0.405
NI
0.0567
-1.6217
31
L
0.342
0.482
0.368
0.370
0.474
0.407
NI
0.0656
-1.5961
32
A
0.372
0.498
0.370
0.426
0.500
0.433
NI
0.0641
-1.2640
33
I
0.298
0.470
0.348
0.360
0.446
0.384
NI
0.0716
-1.8874
34
L
0.334
0.470
0.382
0.396
0.508
0.418
NI
0.0701
-1.4582
35
T
0.356
0.524
0.410
0.424
0.516
0.446
NI
0.0722
-1.1005
36
A
0.440
0.546
0.430
0.472
0.554
0.488
NI
0.0584
-0.5589
37
L
0.448
0.518
0.420
0.418
0.534
0.468
NI
0.0549
-0.8246
38
R
0.438
0.582
0.500
0.532
0.584
0.527
I
0.0611
-0.0632
39
L
0.490
0.502
0.454
0.504
0.524
0.495
NI
0.0259
-0.4771
40
C
0.402
0.536
0.512
0.452
0.570
0.494
NI
0.0673
-0.4822
41
A
0.466
0.490
0.398
0.490
0.554
0.480
NI
0.0561
-0.6713
42
Y
0.474
0.518
0.476
0.542
0.582
0.518
I
0.0457
-0.1756
43
C
0.484
0.510
0.446
0.528
0.532
0.500
NI
0.0356
-0.4107
44
C
0.490
0.492
0.482
0.520
0.586
0.514
I
0.0427
-0.2318
45
N
0.554
0.582
0.486
0.556
0.634
0.562
I
0.0535
0.3864
46
I
0.560
0.540
0.476
0.508
0.582
0.533
I
0.0420
0.0134
47
V
0.530
0.584
0.520
0.430
0.594
0.532
I
0.0654
-0.0070
48
N
0.540
0.626
0.518
0.546
0.684
0.583
I
0.0698
0.6470
49
V
0.554
0.584
0.522
0.504
0.616
0.556
I
0.0454
0.3047
50
S
0.554
0.622
0.544
0.528
0.632
0.576
I
0.0476
0.5602
51
L
0.520
0.626
0.508
0.506
0.610
0.554
I
0.0589
0.2791
52
V
0.494
0.672
0.522
0.482
0.600
0.554
I
0.0804
0.2791
53
K
0.590
0.644
0.518
0.564
0.658
0.595
I
0.0576
0.8003
54
P
0.512
0.608
0.502
0.522
0.614
0.552
I
0.0547
0.2485
55
S
0.482
0.582
0.510
0.508
0.606
0.538
I
0.0533
0.0696
56
F
0.524
0.564
0.530
0.494
0.592
0.541
I
0.0379
0.1105
57
Y
0.556
0.614
0.542
0.560
0.576
0.570
I
0.0276
0.4784
58
V
0.496
0.498
0.502
0.436
0.492
0.485
NI
0.0275
-0.6049
59
Y
0.588
0.574
0.624
0.576
0.550
0.582
I
0.0270
0.6419
60
S
0.632
0.582
0.592
0.544
0.652
0.600
I
0.0426
0.8719
61
R
0.606
0.622
0.576
0.548
0.622
0.595
I
0.0322
0.8003
62
V
0.624
0.628
0.616
0.566
0.622
0.611
I
0.0256
1.0098
63
K
0.634
0.652
0.624
0.656
0.562
0.626
I
0.0379
1.1938
64
N
0.610
0.592
0.620
0.590
0.572
0.597
I
0.0187
0.8259
65
L
0.584
0.604
0.602
0.598
0.572
0.592
I
0.0136
0.7646
66
N
0.614
0.618
0.598
0.640
0.570
0.608
I
0.0260
0.9689
67
S
0.620
0.564
0.606
0.596
0.620
0.601
I
0.0231
0.8821
68
S
0.580
0.564
0.602
0.604
0.602
0.590
I
0.0177
0.7441
69
R
0.626
0.594
0.608
0.586
0.652
0.613
I
0.0265
1.0354
70
V
0.648
0.568
0.572
0.648
0.632
0.614
I
0.0404
1.0405
71
P
0.618
0.612
0.592
0.622
0.588
0.606
I
0.0155
0.9485
(c) IBIVU 2026. If you are experiencing problems with the
site, please contact the webmaster.