In the table below you can see the SeRenDIP example pdb 1YVB chain A Plasmodium falciparum Cysteine Protease
. The table
contains sequence position, prediction scores and classification based on the default cut-off of 0.5 (above is predicted interaction).
Qingzhen Hou1, Reza Haydarlou, Bas Stringer, Katharina Waury, Henriette Capel, Sanne Abeln, Jaap Heringa, K. Anton Feenstra
SeRenDIP-CE: Sequence-based Interface Prediction for Conformational Epitopes
Bioinformatics 37, pp 3421–3427, 2021, doi: 10.1093/bioinformatics/btab321 1Department of Biostatistics, School of Public Health &
National institute of health data science of China; Shandong 250002, P. R. China
Qingzhen Hou1, Paul De Geest, Christian Griffioen, Sanne Abeln,
Jaap Heringa, K. Anton Feenstra.
SeRenDIP: remastered alignment profiles for fast
and accurate predictions of PPI interface positions.Bioinformatics 35, pp 4794–4796, 2019, doi: 10.1093/bioinformatics/btz428 13BIO-BioInfo – BioModeling, BioInformatics & BioProcesses, Université Libre de Bruxelles
Qingzhen Hou, Paul De Geest, Wim F. Vranken, Jaap Heringa and K. Anton Feenstra Seeing the Trees through the Forest:
Sequence-based Homo- and Heteromeric
Protein-protein Interaction sites prediction using
Random Forest. Bioinformatics, 2017, doi: 10.1093/bioinformatics/btx005
Color better than threshold:
Sequence
Heteromeric Prediction
Pos
AA
Model
Pred
x of 233 rows match filter(s)
5
E
0.470
NI
6
E
0.442
NI
7
V
0.370
NI
8
I
0.382
NI
9
K
0.450
NI
10
K
0.432
NI
11
Y
0.430
NI
12
R
0.468
NI
13
G
0.388
NI
14
E
0.472
NI
15
E
0.450
NI
16
N
0.444
NI
17
F
0.458
NI
18
D
0.432
NI
19
H
0.462
NI
20
A
0.486
NI
21
A
0.562
I
22
Y
0.510
I
23
D
0.516
I
24
W
0.378
NI
25
R
0.516
I
26
L
0.492
NI
27
H
0.474
NI
28
S
0.462
NI
29
G
0.484
NI
30
V
0.456
NI
31
T
0.438
NI
32
P
0.490
NI
33
V
0.250
NI
34
K
0.524
I
35
D
0.648
I
36
Q
0.530
I
37
K
0.602
I
38
N
0.694
I
39
C
0.502
I
40
G
0.514
I
41
S
0.414
NI
42
C
0.402
NI
43
W
0.434
NI
44
A
0.184
NI
45
F
0.278
NI
46
S
0.140
NI
47
S
0.214
NI
48
I
0.176
NI
49
G
0.198
NI
50
S
0.272
NI
51
V
0.188
NI
52
E
0.250
NI
53
S
0.204
NI
54
Q
0.484
NI
55
Y
0.462
NI
56
A
0.408
NI
57
I
0.518
I
58
R
0.580
I
59
K
0.550
I
60
N
0.548
I
61
K
0.532
I
62
L
0.518
I
63
I
0.518
I
64
T
0.514
I
65
L
0.348
NI
66
S
0.386
NI
67
E
0.578
I
68
Q
0.532
I
69
E
0.550
I
70
L
0.368
NI
71
V
0.418
NI
72
D
0.398
NI
73
C
0.336
NI
74
S
0.452
NI
75
F
0.556
I
76
K
0.542
I
77
N
0.502
I
78
Y
0.562
I
79
G
0.424
NI
80
C
0.488
NI
81
N
0.576
I
82
G
0.554
I
83
G
0.572
I
84
L
0.648
I
85
I
0.592
I
86
N
0.570
I
87
N
0.554
I
88
A
0.152
NI
89
F
0.240
NI
90
E
0.512
I
91
D
0.498
NI
92
M
0.276
NI
93
I
0.444
NI
94
E
0.514
I
95
L
0.448
NI
96
G
0.436
NI
97
G
0.422
NI
98
I
0.424
NI
99
C
0.454
NI
100
P
0.444
NI
101
D
0.478
NI
102
G
0.522
I
103
D
0.500
NI
104
Y
0.444
NI
105
P
0.448
NI
106
Y
0.422
NI
107
V
0.476
NI
108
S
0.496
NI
109
D
0.430
NI
110
A
0.536
I
111
P
0.586
I
112
N
0.454
NI
113
L
0.486
NI
114
C
0.280
NI
115
N
0.432
NI
116
I
0.408
NI
117
D
0.478
NI
118
R
0.466
NI
119
C
0.386
NI
120
T
0.422
NI
121
E
0.410
NI
122
K
0.458
NI
123
Y
0.316
NI
124
G
0.430
NI
125
I
0.320
NI
126
K
0.492
NI
127
N
0.528
I
128
Y
0.510
I
129
L
0.452
NI
130
S
0.468
NI
131
V
0.430
NI
132
P
0.452
NI
133
D
0.462
NI
134
N
0.402
NI
135
K
0.392
NI
136
L
0.164
NI
137
K
0.332
NI
138
E
0.350
NI
139
A
0.464
NI
140
L
0.166
NI
141
R
0.456
NI
142
F
0.450
NI
143
L
0.424
NI
144
G
0.340
NI
145
P
0.364
NI
146
I
0.278
NI
147
S
0.192
NI
148
I
0.128
NI
149
S
0.140
NI
150
V
0.204
NI
151
A
0.442
NI
152
V
0.404
NI
153
S
0.538
I
154
D
0.634
I
155
D
0.556
I
156
F
0.406
NI
157
A
0.590
I
158
F
0.612
I
159
Y
0.342
NI
160
K
0.652
I
161
E
0.594
I
162
G
0.372
NI
163
I
0.402
NI
164
F
0.390
NI
165
D
0.408
NI
166
G
0.502
I
167
E
0.520
I
168
C
0.478
NI
169
G
0.480
NI
170
D
0.528
I
171
Q
0.514
I
172
L
0.478
NI
173
N
0.522
I
174
H
0.480
NI
175
A
0.398
NI
176
V
0.100
NI
177
M
0.168
NI
178
L
0.104
NI
179
V
0.248
NI
180
G
0.298
NI
181
F
0.380
NI
182
G
0.494
NI
183
M
0.504
I
184
K
0.566
I
185
E
0.530
I
186
I
0.580
I
187
V
0.472
NI
188
N
0.528
I
189
P
0.484
NI
190
L
0.528
I
191
T
0.516
I
192
K
0.480
NI
193
K
0.494
NI
194
G
0.478
NI
195
E
0.456
NI
196
K
0.472
NI
197
H
0.472
NI
198
Y
0.468
NI
199
Y
0.454
NI
200
Y
0.254
NI
201
I
0.250
NI
202
I
0.132
NI
203
K
0.344
NI
204
N
0.366
NI
205
S
0.492
NI
206
W
0.630
I
207
G
0.524
I
208
Q
0.602
I
209
Q
0.680
I
210
W
0.596
I
211
G
0.536
I
212
E
0.430
NI
213
R
0.494
NI
214
G
0.324
NI
215
F
0.392
NI
216
I
0.102
NI
217
N
0.396
NI
218
I
0.150
NI
219
E
0.500
NI
220
T
0.544
I
221
D
0.530
I
222
E
0.544
I
223
S
0.522
I
224
G
0.534
I
225
L
0.560
I
226
M
0.566
I
227
R
0.474
NI
228
K
0.500
NI
229
C
0.354
NI
230
G
0.324
NI
231
L
0.318
NI
232
G
0.420
NI
233
T
0.450
NI
234
D
0.564
I
235
A
0.406
NI
236
F
0.516
I
237
I
0.470
NI
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