sidebar-main
title
griff
banner-button_0 banner-button_Layer-7 banner_button_03 banner-button_Layer-4 banner-button_05 banner-button_Layer-5 banner-button_07
banner-button_08 banner-button_09 banner-button_10
Bioinformatics Unit banner
   homeoffresearchoffconfoffprogonmemoffpuboffvacoff
   tabfoot tabfoot-bgtabfoot-bgtabfoot-bgtabfoot-bgtabfoot-bgtabfoot-bgtabfoot-bgtabfoot-bgtabfoot-bgtabfoot-bgtabfoot-bgtabfoot-bgtabfoot-bgtabfoot-bgtabfoot-bg

Scooby-domain prediction

Please do not link this web address!
For stable links, please refer to www.ibi.vu.nl/programs/ or www.ibi.vu.nl/programs/scoobywww/index.php.
scooby logo

Scooby-domain (Sequence hydrophobicity predicts domains) is a method to identify globular regions in protein sequence that are suitable for structural studies. The current version is 2.0. Note however, that the JAVA applet runs version 1.0. The Scooby-domain JAVA applet (v1.0) can be used as a tool to visually identify 'foldable' regions in protein sequence.

Documentation.

cog WSDL: SOAP interface available.

References:
George RA, Lin K and Heringa J. (2005) Scooby-domain: prediction of globular domains in protein sequence. 2005. Nucleic Acids Research 33: W160-163.

Pang CN, Lin K, Wouters MA, Heringa J, George RA. (2008) Identifying foldable regions in protein sequence from the hydrophobic signal. Nucleic Acids Research 36: 578-588.

Paste in a protein sequence or alignment in fasta format:*


Or Upload a sequence:


Or Supply a UniProt ID:


Include your own linker annotation file:


Use DomCut on first sequence only (recommended)
Use DomCut on all sequences
Do not use DomCut

  

*Note: allowed gap symbols are "." and "-". Gap symbols in a single sequence will not be deleted.
 

The ScoobyDo web server was developed by Richard George. Updated & maintained by Bernd Brandt.

(c) IBIVU 2026. If you are experiencing problems with the site, please contact the webmaster.
503 Service Unavailable

Service Unavailable

The server is temporarily unable to service your request due to maintenance downtime or capacity problems. Please try again later.