Supply your alignment in FASTA, Clustal, MSF, SELEX or Stockholm format. Supply groupings of all sequences in your alignment in 'groups' as comma, or white-space seperated list. The URL can be used to see the results with your web browser. If you append "file" of the predictor to this URL you can access the text output directly. WSDL File for multi-Harmony Specificity Determining Position Prediction Documentation on: http://www.ibi.vu.nl/programs/shmrwww/