This is SeqHarmMulti.py 4.0b Webserver at http://www.ibi.vu.nl/programs/shmrwww/ Please cite: Bernd Brandt*, K. Anton Feenstra* and Jaap Heringa "Multi-Harmony: detecting functional specificity from sequence alignment" Nucl. Acids Res., 2010, submitted * joint first authors. Calculating Sequence Harmony include end gaps; include unknown residues ('X') Found 33 sequences We now have 5 groups: group 1: 9 sequences label: 1(9) 1 1 gi|7160686|emb|CAB76819.1|/1-465 2 2 gi|61967924|gb|AAX56944.1|/1-465 3 3 gi|11464653|gb|AAG35265.1|/1-455 4 4 gi|6273783|gb|AAF06361.1|/1-472 5 5 gi|11907945|gb|AAG41407.1|/1-465 6 6 gi|29725652|gb|AAO88909.1|/1-465 7 7 gi|1654323|gb|AAC50790.1|/1-465 8 8 gi|3192871|gb|AAC19116.1|/1-468 9 9 gi|55926152|ref|NP_001007481.1|/1-464 group 2: 5 sequences label: 2(5) 10 1 gi|61967926|gb|AAX56945.1|/1-465 11 2 gi|2360958|gb|AAB92396.1|/1-465 12 3 gi|5706366|dbj|BAA83093.1|/1-465 13 4 gi|3982649|gb|AAC83580.1|/1-465 14 5 gi|6288777|gb|AAF06738.1|/1-464 group 3: 3 sequences label: 3(3) 15 1 gi|61967928|gb|AAX56946.1|/1-476 16 2 gi|2689629|gb|AAC53515.1|/1-434 17 3 gi|22532988|gb|AAF77079.2|/1-428 group 4: 8 sequences label: 4(8) 18 1 gi|2967646|gb|AAC39657.1|/1-467 19 2 gi|45331050|gb|AAS57861.1|/1-468 20 3 gi|5360217|dbj|BAA81909.1|/1-467 21 4 gi|6288775|gb|AAF06737.1|/1-468 22 5 gi|58047721|gb|AAH89184.1|/1-467 23 6 gi|4009524|gb|AAD11458.1|/1-486 24 7 gi|40254710|ref|NP_571441.2|/1-468 25 8 gi|18655485|pdb|1KHX|A|/22-226 group 5: 8 sequences label: 5(8) 26 1 gi|13992583|emb|CAC38118.1|/1-425 27 2 gi|11875329|dbj|BAB19634.1|/1-425 28 3 gi|45331052|gb|AAS57862.1|/1-422 29 4 gi|18418623|gb|AAL68976.1|/1-425 30 5 gi|2564493|gb|AAB81755.1|/1-425 31 6 gi|6981174|ref|NP_037227.1|/1-425 32 7 gi|45383213|ref|NP_989806.1|/1-426 33 8 gi|47523074|ref|NP_999302.1|/1-425 Generalized Harmonies with modified p log p for N groups Will do 100 randomizations of 5 groups [9, 5, 3, 8, 8]: calculated 0 out of 100 randomizations (0%) calculated 1 out of 100 randomizations (1%) calculated 2 out of 100 randomizations (2%) calculated 3 out of 100 randomizations (3%) calculated 4 out of 100 randomizations (4%) calculated 5 out of 100 randomizations (5%) calculated 6 out of 100 randomizations (6%) calculated 7 out of 100 randomizations (7%) calculated 8 out of 100 randomizations (8%) calculated 9 out of 100 randomizations (9%) calculated 10 out of 100 randomizations (10%) calculated 11 out of 100 randomizations (11%) calculated 12 out of 100 randomizations (12%) calculated 13 out of 100 randomizations (13%) calculated 14 out of 100 randomizations (14%) calculated 15 out of 100 randomizations (15%) calculated 16 out of 100 randomizations (16%) calculated 17 out of 100 randomizations (17%) calculated 18 out of 100 randomizations (18%) calculated 19 out of 100 randomizations (19%) calculated 20 out of 100 randomizations (20%) calculated 21 out of 100 randomizations (21%) calculated 22 out of 100 randomizations (22%) calculated 23 out of 100 randomizations (23%) calculated 24 out of 100 randomizations (24%) calculated 25 out of 100 randomizations (25%) calculated 26 out of 100 randomizations (26%) calculated 27 out of 100 randomizations (27%) calculated 28 out of 100 randomizations (28%) calculated 29 out of 100 randomizations (29%) calculated 30 out of 100 randomizations (30%) calculated 31 out of 100 randomizations (31%) calculated 32 out of 100 randomizations (32%) calculated 33 out of 100 randomizations (33%) calculated 34 out of 100 randomizations (34%) calculated 35 out of 100 randomizations (35%) calculated 36 out of 100 randomizations (36%) calculated 37 out of 100 randomizations (37%) calculated 38 out of 100 randomizations (38%) calculated 39 out of 100 randomizations (39%) calculated 40 out of 100 randomizations (40%) calculated 41 out of 100 randomizations (41%) calculated 42 out of 100 randomizations (42%) calculated 43 out of 100 randomizations (43%) calculated 44 out of 100 randomizations (44%) calculated 45 out of 100 randomizations (45%) calculated 46 out of 100 randomizations (46%) calculated 47 out of 100 randomizations (47%) calculated 48 out of 100 randomizations (48%) calculated 49 out of 100 randomizations (49%) calculated 50 out of 100 randomizations (50%) calculated 51 out of 100 randomizations (51%) calculated 52 out of 100 randomizations (52%) calculated 53 out of 100 randomizations (53%) calculated 54 out of 100 randomizations (54%) calculated 55 out of 100 randomizations (55%) calculated 56 out of 100 randomizations (56%) calculated 57 out of 100 randomizations (57%) calculated 58 out of 100 randomizations (58%) calculated 59 out of 100 randomizations (59%) calculated 60 out of 100 randomizations (60%) calculated 61 out of 100 randomizations (61%) calculated 62 out of 100 randomizations (62%) calculated 63 out of 100 randomizations (63%) calculated 64 out of 100 randomizations (64%) calculated 65 out of 100 randomizations (65%) calculated 66 out of 100 randomizations (66%) calculated 67 out of 100 randomizations (67%) calculated 68 out of 100 randomizations (68%) calculated 69 out of 100 randomizations (69%) calculated 70 out of 100 randomizations (70%) calculated 71 out of 100 randomizations (71%) calculated 72 out of 100 randomizations (72%) calculated 73 out of 100 randomizations (73%) calculated 74 out of 100 randomizations (74%) calculated 75 out of 100 randomizations (75%) calculated 76 out of 100 randomizations (76%) calculated 77 out of 100 randomizations (77%) calculated 78 out of 100 randomizations (78%) calculated 79 out of 100 randomizations (79%) calculated 80 out of 100 randomizations (80%) calculated 81 out of 100 randomizations (81%) calculated 82 out of 100 randomizations (82%) calculated 83 out of 100 randomizations (83%) calculated 84 out of 100 randomizations (84%) calculated 85 out of 100 randomizations (85%) calculated 86 out of 100 randomizations (86%) calculated 87 out of 100 randomizations (87%) calculated 88 out of 100 randomizations (88%) calculated 89 out of 100 randomizations (89%) calculated 90 out of 100 randomizations (90%) calculated 91 out of 100 randomizations (91%) calculated 92 out of 100 randomizations (92%) calculated 93 out of 100 randomizations (93%) calculated 94 out of 100 randomizations (94%) calculated 95 out of 100 randomizations (95%) calculated 96 out of 100 randomizations (96%) calculated 97 out of 100 randomizations (97%) calculated 98 out of 100 randomizations (98%) calculated 99 out of 100 randomizations (99%) Done. Output Sequence Harmonies Alignment Position Sequence Harmony Z_scores Total Entropy 1(9) Entropies 1(9) Consensus string 2(5) Entropies 2(5) Consensus string 3(3) Entropies 3(3) Consensus string 4(8) Entropies 4(8) Consensus string 5(8) Entropies 5(8) Consensus string 1 0.905013 -2.40460402211 0.0 0.15876 Dt 0.0 D 0.57938 ND 0.0 D 0.0 D 2 0.323279 -11.333548958 0.0 0.15876 Vm 0.0 V 0.0 F 0.181188 La 0.0 L 3 0.626857 -8.33726391875 0.0 0.24108 Qh 0.0 Q 0.0 R 0.181188 Qa 0.0 Q 4 0.797268 -4.43940806532 0.0 0.24108 Ap 0.0 P 0.0 P 0.0 P 0.0 P 5 1.0 nan 0.0 0.0 V 0.0 V 0.0 V 0.0 V 0.0 V 6 0.306168 -10.8516335608 0.0 0.15876 An 0.310918 Ae 0.0 C 0.181188 Tm 0.0 T 7 1.0 nan 0.0 0.0 Y 0.0 Y 0.0 Y 0.0 Y 0.0 Y 8 0.386101 -9.64148925301 0.0 0.24108 Eq 0.310918 Eq 0.0 E 0.181188 Sh 0.0 C 9 1.0 nan 0.0 0.0 E 0.0 E 0.0 E 0.0 E 0.0 E 10 0.974182 0.491885482625 0.123753 0.0 P 0.0 P 0.0 P 0.0 P 0.181188 Ps 11 0.325931 -11.2453695382 0.0 0.0 K 0.310918 Ks 0.57938 LQ 0.0 A 0.0 A 12 0.566127 -7.99282148976 0.0 0.15876 Hy 0.0 H 0.0 H 0.0 F 0.0 F 13 1.0 nan 0.0 0.0 W 0.0 W 0.0 W 0.0 W 0.0 W 14 1.0 nan 0.0 0.0 C 0.0 C 0.0 C 0.0 C 0.0 C 15 1.0 nan 0.0 0.0 S 0.0 S 0.0 S 0.0 S 0.0 S 16 0.689082 -14.058214923 0.0 0.0 I 0.0 I 0.0 V 0.0 I 0.0 I 17 0.382023 -11.4894602812 0.0 0.0 V 0.0 V 0.0 A 0.181188 As 0.0 S 18 1.0 nan 0.0 0.0 Y 0.0 Y 0.0 Y 0.0 Y 0.0 Y 19 1.0 nan 0.0 0.0 Y 0.0 Y 0.0 Y 0.0 Y 0.0 Y 20 1.0 nan 0.0 0.0 E 0.0 E 0.0 E 0.0 E 0.0 E 21 1.0 nan 0.0 0.0 L 0.0 L 0.0 L 0.0 L 0.0 L 22 1.0 nan 0.0 0.0 N 0.0 N 0.0 N 0.0 N 0.0 N 23 0.570549 -8.10487428118 0.0 0.0 N 0.0 N 0.0 N 0.181188 Qt 0.0 Q 24 1.0 nan 0.0 0.0 R 0.0 R 0.0 R 0.0 R 0.0 R 25 1.0 nan 0.0 0.0 V 0.0 V 0.0 V 0.0 V 0.0 V 26 1.0 nan 0.0 0.0 G 0.0 G 0.0 G 0.0 G 0.0 G 27 1.0 nan 0.0 0.0 E 0.0 E 0.0 E 0.0 E 0.0 E 28 0.581834 -9.04438717881 0.0 0.0 A 0.0 A 0.0 T 0.0 T 0.0 T 29 0.957834 -0.565403133995 0.0 0.0 F 0.310918 Fy 0.0 F 0.0 F 0.0 F 30 0.648257 -10.6269921361 0.0 0.311183 Hln 0.0 H 0.0 Q 0.0 H 0.0 H 31 1.0 nan 0.0 0.0 A 0.0 A 0.0 A 0.0 A 0.0 A 32 1.0 nan 0.0 0.0 S 0.0 S 0.0 S 0.0 S 0.0 S 33 0.62022 -7.71244657671 0.0 0.15876 Sq 0.0 S 0.0 S 0.0 Q 0.0 Q 34 0.334564 -11.6496050419 0.0 0.15876 Tl 0.0 T 0.0 R 0.0 P 0.0 P 35 1.0 nan 0.0 0.0 S 0.0 S 0.0 S 0.0 S 0.0 S 36 0.460013 -7.54964163722 0.123753 0.28969 IV 0.0 V 0.57938 IV 0.181188 Li 0.181188 Ml 37 0.566127 -7.99282148976 0.0 0.15876 Li 0.0 L 0.0 L 0.0 T 0.0 T 38 0.714223 -13.8419366709 0.0 0.15876 Vi 0.0 V 0.0 I 0.0 V 0.0 V 39 1.0 nan 0.0 0.0 D 0.0 D 0.0 D 0.0 D 0.0 D 40 1.0 nan 0.0 0.0 G 0.0 G 0.0 G 0.0 G 0.0 G 41 1.0 nan 0.0 0.0 F 0.0 F 0.0 F 0.0 F 0.0 F 42 1.0 nan 0.0 0.0 T 0.0 T 0.0 T 0.0 T 0.0 T 43 1.0 nan 0.0 0.0 D 0.0 D 0.0 D 0.0 D 0.0 D 44 1.0 nan 0.0 0.0 P 0.0 P 0.0 P 0.0 P 0.0 P 45 0.957834 -0.533385143781 0.0 0.0 S 0.310918 Sa 0.0 S 0.0 S 0.0 S 46 1.0 nan 0.0 0.0 N 0.0 N 0.0 N 0.0 N 0.0 N 47 0.570549 -7.1765080739 0.123753 0.0 N 0.0 N 0.0 N 0.0 S 0.181188 Sa 48 0.485754 -8.34295775663 0.0 0.386253 Ksr 0.0 K 0.57938 KR 0.0 - 0.0 - 49 0.466356 -8.95237157052 0.0 0.15876 Nd 0.418166 NS 0.0 N 0.0 E 0.0 E 50 1.0 nan 0.0 0.0 R 0.0 R 0.0 R 0.0 R 0.0 R 51 0.974182 0.337556403966 0.123753 0.0 F 0.0 F 0.0 F 0.0 F 0.181188 Fl 52 1.0 nan 0.0 0.0 C 0.0 C 0.0 C 0.0 C 0.0 C 53 1.0 nan 0.0 0.0 L 0.0 L 0.0 L 0.0 L 0.0 L 54 0.974182 0.396735046392 0.0 0.0 G 0.0 G 0.0 G 0.181188 Gc 0.0 G 55 1.0 nan 0.0 0.0 L 0.0 L 0.0 L 0.0 L 0.0 L 56 1.0 nan 0.0 0.0 L 0.0 L 0.0 L 0.0 L 0.0 L 57 1.0 nan 0.0 0.0 S 0.0 S 0.0 S 0.0 S 0.0 S 58 1.0 nan 0.0 0.0 N 0.0 N 0.0 N 0.0 N 0.0 N 59 1.0 nan 0.0 0.0 V 0.0 V 0.0 V 0.0 V 0.0 V 60 1.0 nan 0.0 0.0 N 0.0 N 0.0 N 0.0 N 0.0 N 61 1.0 nan 0.0 0.0 R 0.0 R 0.0 R 0.0 R 0.0 R 62 1.0 nan 0.0 0.0 N 0.0 N 0.0 N 0.0 N 0.0 N 63 0.570549 -8.10487428118 0.0 0.0 S 0.0 S 0.0 S 0.181188 Ae 0.0 A 64 0.66678 -6.840799324 0.0 0.0 T 0.0 T 0.0 T 0.181188 Tv 0.0 A 65 0.581834 -8.46055849692 0.0 0.0 I 0.0 I 0.0 I 0.0 V 0.0 V 66 1.0 nan 0.0 0.0 E 0.0 E 0.0 E 0.0 E 0.0 E 67 0.409564 -10.8888886309 0.0 0.0 N 0.0 N 0.0 N 0.181188 Mq 0.0 L 68 1.0 nan 0.0 0.0 T 0.0 T 0.0 T 0.0 T 0.0 T 69 1.0 nan 0.0 0.0 R 0.0 R 0.0 R 0.0 R 0.0 R 70 1.0 nan 0.0 0.0 R 0.0 R 0.0 R 0.0 R 0.0 R 71 1.0 nan 0.0 0.0 H 0.0 H 0.0 H 0.0 H 0.0 H 72 1.0 nan 0.0 0.0 I 0.0 I 0.0 I 0.0 I 0.0 I 73 1.0 nan 0.0 0.0 G 0.0 G 0.0 G 0.0 G 0.0 G 74 0.635768 -7.79220398399 0.0 0.0 K 0.0 K 0.0 K 0.181188 Rk 0.0 R 75 1.0 nan 0.0 0.0 G 0.0 G 0.0 G 0.0 G 0.0 G 76 1.0 nan 0.0 0.0 V 0.0 V 0.0 V 0.0 V 0.0 V 77 0.581834 -8.46055849692 0.0 0.0 H 0.0 H 0.0 H 0.0 R 0.0 R 78 1.0 nan 0.0 0.0 L 0.0 L 0.0 L 0.0 L 0.0 L 79 1.0 nan 0.0 0.0 Y 0.0 Y 0.0 Y 0.0 Y 0.0 Y 80 1.0 nan 0.0 0.0 Y 0.0 Y 0.0 Y 0.0 Y 0.0 Y 81 0.581834 -8.46055849692 0.0 0.0 V 0.0 V 0.0 V 0.0 I 0.0 I 82 1.0 nan 0.0 0.0 G 0.0 G 0.0 G 0.0 G 0.0 G 83 1.0 nan 0.0 0.0 G 0.0 G 0.0 G 0.0 G 0.0 G 84 1.0 nan 0.0 0.0 E 0.0 E 0.0 E 0.0 E 0.0 E 85 1.0 nan 0.0 0.0 V 0.0 V 0.0 V 0.0 V 0.0 V 86 0.581834 -8.46055849692 0.0 0.0 Y 0.0 Y 0.0 Y 0.0 F 0.0 F 87 1.0 nan 0.0 0.0 A 0.0 A 0.0 A 0.0 A 0.0 A 88 1.0 nan 0.0 0.0 E 0.0 E 0.0 E 0.0 E 0.0 E 89 1.0 nan 0.0 0.0 C 0.0 C 0.0 C 0.0 C 0.0 C 90 0.689082 -14.058214923 0.0 0.0 L 0.0 L 0.0 V 0.0 L 0.0 L 91 1.0 nan 0.0 0.0 S 0.0 S 0.0 S 0.0 S 0.0 S 92 1.0 nan 0.0 0.0 D 0.0 D 0.0 D 0.0 D 0.0 D 93 0.932658 -0.000340652883149 0.123753 0.0 S 0.310918 St 0.0 S 0.0 S 0.181188 Sn 94 0.635768 -7.79220398399 0.0 0.0 S 0.0 S 0.0 S 0.181188 As 0.0 A 95 1.0 nan 0.0 0.0 I 0.0 I 0.0 I 0.0 I 0.0 I 96 1.0 nan 0.0 0.0 F 0.0 F 0.0 F 0.0 F 0.0 F 97 1.0 nan 0.0 0.0 V 0.0 V 0.0 V 0.0 V 0.0 V 98 1.0 nan 0.0 0.0 Q 0.0 Q 0.0 Q 0.0 Q 0.0 Q 99 1.0 nan 0.0 0.0 S 0.0 S 0.0 S 0.0 S 0.0 S 100 0.581834 -8.46055849692 0.0 0.0 R 0.0 R 0.0 R 0.0 P 0.0 P 101 1.0 nan 0.0 0.0 N 0.0 N 0.0 N 0.0 N 0.0 N 102 1.0 nan 0.0 0.0 C 0.0 C 0.0 C 0.0 C 0.0 C 103 1.0 nan 0.0 0.0 N 0.0 N 0.0 N 0.0 N 0.0 N 104 0.504655 -8.09752122361 0.0 0.15876 Yf 0.418166 YF 0.0 Y 0.0 Q 0.0 Q 105 0.344541 -12.0673451317 0.0 0.0 H 0.0 H 0.0 Q 0.0 R 0.0 R 106 0.581834 -8.46055849692 0.0 0.0 H 0.0 H 0.0 H 0.0 Y 0.0 Y 107 0.951671 0.649319003357 0.0 0.15876 Gn 0.0 G 0.0 G 0.181188 Gd 0.0 G 108 0.581834 -8.46055849692 0.0 0.0 F 0.0 F 0.0 F 0.0 W 0.0 W 109 1.0 nan 0.0 0.0 H 0.0 H 0.0 H 0.0 H 0.0 H 110 1.0 nan 0.0 0.0 P 0.0 P 0.0 P 0.0 P 0.0 P 111 0.581834 -9.04438717881 0.0 0.0 T 0.0 T 0.0 A 0.0 A 0.0 A 112 1.0 nan 0.0 0.0 T 0.0 T 0.0 T 0.0 T 0.0 T 113 1.0 nan 0.0 0.0 V 0.0 V 0.0 V 0.0 V 0.0 V 114 1.0 nan 0.0 0.0 C 0.0 C 0.0 C 0.0 C 0.0 C 115 1.0 nan 0.0 0.0 K 0.0 K 0.0 K 0.0 K 0.0 K 116 1.0 nan 0.0 0.0 I 0.0 I 0.0 I 0.0 I 0.0 I 117 1.0 nan 0.0 0.0 P 0.0 P 0.0 P 0.0 P 0.0 P 118 0.62022 -7.71244657671 0.0 0.15876 Sp 0.0 S 0.0 S 0.0 P 0.0 P 119 0.834571 -3.50004853896 0.0 0.15876 Gr 0.418166 GS 0.0 G 0.0 G 0.0 G 120 1.0 nan 0.0 0.0 C 0.0 C 0.0 C 0.0 C 0.0 C 121 0.581834 -8.46055849692 0.0 0.0 S 0.0 S 0.0 S 0.0 N 0.0 N 122 1.0 nan 0.0 0.0 L 0.0 L 0.0 L 0.0 L 0.0 L 123 1.0 nan 0.0 0.0 K 0.0 K 0.0 K 0.0 K 0.0 K 124 0.835115 -9.34714409978 0.0 0.0 I 0.0 I 0.57938 IV 0.0 I 0.0 I 125 1.0 nan 0.0 0.0 F 0.0 F 0.0 F 0.0 F 0.0 F 126 0.977135 0.514525788279 0.0 0.15876 Ns 0.0 N 0.0 N 0.0 N 0.0 N 127 1.0 nan 0.0 0.0 N 0.0 N 0.0 N 0.0 N 0.0 N 128 1.0 nan 0.0 0.0 Q 0.0 Q 0.0 Q 0.0 Q 0.0 Q 129 0.689082 -14.058214923 0.0 0.0 E 0.0 E 0.0 L 0.0 E 0.0 E 130 1.0 nan 0.0 0.0 F 0.0 F 0.0 F 0.0 F 0.0 F 131 0.926914 -3.85674047347 0.0 0.0 - 0.0 - 0.57938 A- 0.0 - 0.0 - 132 0.926914 -3.85674047347 0.0 0.0 - 0.0 - 0.57938 Q- 0.0 - 0.0 - 133 0.926914 -3.85674047347 0.0 0.0 - 0.0 - 0.57938 L- 0.0 - 0.0 - 134 0.926914 -3.85674047347 0.0 0.0 - 0.0 - 0.57938 L- 0.0 - 0.0 - 135 1.0 nan 0.0 0.0 A 0.0 A 0.0 A 0.0 A 0.0 A 136 0.54922 -7.75370877547 0.0 0.311183 Qeh 0.0 Q 0.0 Q 0.0 A 0.0 A 137 0.926914 -3.39239390809 0.0 0.0 L 0.0 L 0.57938 PL 0.0 L 0.0 L 138 1.0 nan 0.0 0.0 L 0.0 L 0.0 L 0.0 L 0.0 L 139 0.971957 0.841191297218 0.0 0.15876 As 0.0 A 0.0 A 0.181188 As 0.0 A 140 0.977135 0.514525788279 0.0 0.15876 Qr 0.0 Q 0.0 Q 0.0 Q 0.0 Q 141 0.977135 0.514525788279 0.0 0.15876 St 0.0 S 0.0 S 0.0 S 0.0 S 142 1.0 nan 0.0 0.0 V 0.0 V 0.0 V 0.0 V 0.0 V 143 0.830733 -4.46131784965 0.0 0.15876 Nh 0.0 N 0.57938 NH 0.181188 Ns 0.0 N 144 0.581834 -8.46055849692 0.0 0.0 H 0.0 H 0.0 H 0.0 Q 0.0 Q 145 1.0 nan 0.0 0.0 G 0.0 G 0.0 G 0.0 G 0.0 G 146 1.0 nan 0.0 0.0 F 0.0 F 0.0 F 0.0 F 0.0 F 147 1.0 nan 0.0 0.0 E 0.0 E 0.0 E 0.0 E 0.0 E 148 0.51005 -10.0706074649 0.0 0.24108 Ta 0.0 A 0.0 V 0.0 A 0.0 A 149 1.0 nan 0.0 0.0 V 0.0 V 0.0 V 0.0 V 0.0 V 150 1.0 nan 0.0 0.0 Y 0.0 Y 0.0 Y 0.0 Y 0.0 Y 151 0.570549 -7.1765080739 0.123753 0.0 E 0.0 E 0.0 E 0.0 Q 0.181188 Qr 152 1.0 nan 0.0 0.0 L 0.0 L 0.0 L 0.0 L 0.0 L 153 1.0 nan 0.0 0.0 T 0.0 T 0.0 T 0.0 T 0.0 T 154 0.581834 -8.46055849692 0.0 0.0 K 0.0 K 0.0 K 0.0 R 0.0 R 155 1.0 nan 0.0 0.0 M 0.0 M 0.0 M 0.0 M 0.0 M 156 1.0 nan 0.0 0.0 C 0.0 C 0.0 C 0.0 C 0.0 C 157 1.0 nan 0.0 0.0 T 0.0 T 0.0 T 0.0 T 0.0 T 158 0.952854 -0.226788897935 0.0 0.24108 Il 0.0 I 0.0 I 0.0 I 0.0 I 159 1.0 nan 0.0 0.0 R 0.0 R 0.0 R 0.0 R 0.0 R 160 1.0 nan 0.0 0.0 M 0.0 M 0.0 M 0.0 M 0.0 M 161 1.0 nan 0.0 0.0 S 0.0 S 0.0 S 0.0 S 0.0 S 162 1.0 nan 0.0 0.0 F 0.0 F 0.0 F 0.0 F 0.0 F 163 1.0 nan 0.0 0.0 V 0.0 V 0.0 V 0.0 V 0.0 V 164 1.0 nan 0.0 0.0 K 0.0 K 0.0 K 0.0 K 0.0 K 165 1.0 nan 0.0 0.0 G 0.0 G 0.0 G 0.0 G 0.0 G 166 1.0 nan 0.0 0.0 W 0.0 W 0.0 W 0.0 W 0.0 W 167 1.0 nan 0.0 0.0 G 0.0 G 0.0 G 0.0 G 0.0 G 168 1.0 nan 0.0 0.0 A 0.0 A 0.0 A 0.0 A 0.0 A 169 0.977135 0.558032245964 0.0 0.15876 Ek 0.0 E 0.0 E 0.0 E 0.0 E 170 1.0 nan 0.0 0.0 Y 0.0 Y 0.0 Y 0.0 Y 0.0 Y 171 0.581834 -8.46055849692 0.0 0.0 H 0.0 H 0.0 H 0.0 R 0.0 R 172 1.0 nan 0.0 0.0 R 0.0 R 0.0 R 0.0 R 0.0 R 173 1.0 nan 0.0 0.0 Q 0.0 Q 0.0 Q 0.0 Q 0.0 Q 174 0.581834 -8.46055849692 0.0 0.0 D 0.0 D 0.0 D 0.0 T 0.0 T 175 1.0 nan 0.0 0.0 V 0.0 V 0.0 V 0.0 V 0.0 V 176 1.0 nan 0.0 0.0 T 0.0 T 0.0 T 0.0 T 0.0 T 177 1.0 nan 0.0 0.0 S 0.0 S 0.0 S 0.0 S 0.0 S 178 1.0 nan 0.0 0.0 T 0.0 T 0.0 T 0.0 T 0.0 T 179 1.0 nan 0.0 0.0 P 0.0 P 0.0 P 0.0 P 0.0 P 180 1.0 nan 0.0 0.0 C 0.0 C 0.0 C 0.0 C 0.0 C 181 1.0 nan 0.0 0.0 W 0.0 W 0.0 W 0.0 W 0.0 W 182 0.977135 0.514525788279 0.0 0.15876 Iv 0.0 I 0.0 I 0.0 I 0.0 I 183 1.0 nan 0.0 0.0 E 0.0 E 0.0 E 0.0 E 0.0 E 184 0.552708 -7.64925619713 0.0 0.0 I 0.310918 Iv 0.0 I 0.0 L 0.0 L 185 1.0 nan 0.0 0.0 H 0.0 H 0.0 H 0.0 H 0.0 H 186 1.0 nan 0.0 0.0 L 0.0 L 0.0 L 0.0 L 0.0 L 187 0.62022 -7.71244657671 0.0 0.15876 Hn 0.0 H 0.0 H 0.0 N 0.0 N 188 1.0 nan 0.0 0.0 G 0.0 G 0.0 G 0.0 G 0.0 G 189 1.0 nan 0.0 0.0 P 0.0 P 0.0 P 0.0 P 0.0 P 190 1.0 nan 0.0 0.0 L 0.0 L 0.0 L 0.0 L 0.0 L 191 1.0 nan 0.0 0.0 Q 0.0 Q 0.0 Q 0.0 Q 0.0 Q 192 1.0 nan 0.0 0.0 W 0.0 W 0.0 W 0.0 W 0.0 W 193 1.0 nan 0.0 0.0 L 0.0 L 0.0 L 0.0 L 0.0 L 194 1.0 nan 0.0 0.0 D 0.0 D 0.0 D 0.0 D 0.0 D 195 0.971957 0.841191297218 0.0 0.15876 Kr 0.0 K 0.0 K 0.181188 Kr 0.0 K 196 1.0 nan 0.0 0.0 V 0.0 V 0.0 V 0.0 V 0.0 V 197 1.0 nan 0.0 0.0 L 0.0 L 0.0 L 0.0 L 0.0 L 198 1.0 nan 0.0 0.0 T 0.0 T 0.0 T 0.0 T 0.0 T 199 1.0 nan 0.0 0.0 Q 0.0 Q 0.0 Q 0.0 Q 0.0 Q 200 1.0 nan 0.0 0.0 M 0.0 M 0.0 M 0.0 M 0.0 M 201 1.0 nan 0.0 0.0 G 0.0 G 0.0 G 0.0 G 0.0 G 202 0.977135 0.514525788279 0.0 0.15876 St 0.0 S 0.0 S 0.0 S 0.0 S 203 1.0 nan 0.0 0.0 P 0.0 P 0.0 P 0.0 P 0.0 P 204 0.333317 -9.65869469306 0.123753 0.15876 Hr 0.0 L 0.0 H 0.181188 Sr 0.181188 Sn 205 0.431098 -9.56219988905 0.123753 0.0 N 0.0 N 0.0 N 0.181188 Vl 0.181188 Il 206 0.635768 -7.79220398399 0.0 0.0 P 0.0 P 0.0 P 0.181188 Rp 0.0 R 207 0.581834 -8.46055849692 0.0 0.0 I 0.0 I 0.0 I 0.0 C 0.0 C 208 1.0 nan 0.0 0.0 S 0.0 S 0.0 S 0.0 S 0.0 S 209 1.0 nan 0.0 0.0 S 0.0 S 0.0 S 0.0 S 0.0 S 210 0.689082 -8.85596491916 0.0 0.0 V 0.0 V 0.0 V 0.0 M 0.0 V 211 1.0 nan 0.0 0.0 S 0.0 S 0.0 S 0.0 S 0.0 S