Generated on Tue 27 Mar 2007 15:20 by SeqHarm version 1.1
from the Sequence Harmony Webserver at http://www.ibi.vu.nl/programs/seqharmwww/
Please cite:
Walter Pirovano*, K. Anton Feenstra* and Jaap Heringa
"Sequence Comparison by Sequence Harmony Identifies Subtype Specific Functional Sites"
Nucl. Acids Res., 2006, Vol. 34, No. 22 6540-6548
* joint first authors.
Found reference sequence '2_1KHX', offset=1.
Group A: 17 sequences, length 211
Sequences: 1_gi|7160686|emb|CAB76819.1|/1-465, 1_gi|61967924|gb|AAX56944.1|/1-465, 1_gi|11464653|gb|AAG35265.1|AF215933_1/1-455, 1_gi|6273783|gb|AAF06361.1|/1-472, 1_gi|11907945|gb|AAG41407.1|/1-465, 1_gi|29725652|gb|AAO88909.1|/1-465, 1_gi|1654323|gb|AAC50790.1|/1-465, 1_gi|3192871|gb|AAC19116.1|/1-468, 1_gi|55926152|ref|NP_001007481.1|/1-464, 5_gi|61967926|gb|AAX56945.1|/1-465, 5_gi|2360958|gb|AAB92396.1|/1-465, 5_gi|5706366|dbj|BAA83093.1|/1-465, 5_gi|3982649|gb|AAC83580.1|/1-465, 5_gi|6288777|gb|AAF06738.1|/1-464, 8_gi|61967928|gb|AAX56946.1|/1-476, 8_gi|2689629|gb|AAC53515.1|/1-434, 8_gi|22532988|gb|AAF77079.2|AF175408_1/1-428
Group B: 16 sequences, length 211
Sequences: 2_gi|2967646|gb|AAC39657.1|/1-467, 2_gi|45331050|gb|AAS57861.1|/1-468, 2_gi|5360217|dbj|BAA81909.1|/1-467, 2_gi|6288775|gb|AAF06737.1|/1-468, 2_gi|58047721|gb|AAH89184.1|/1-467, 2_gi|4009524|gb|AAD11458.1|/1-486, 2_gi|40254710|ref|NP_571441.2|/1-468, 2_1KHX, 3_gi|13992583|emb|CAC38118.1|/1-425, 3_gi|11875329|dbj|BAB19634.1|/1-425, 3_gi|45331052|gb|AAS57862.1|/1-422, 3_gi|18418623|gb|AAL68976.1|/1-425, 3_gi|2564493|gb|AAB81755.1|/1-425, 3_gi|6981174|ref|NP_037227.1|/1-425, 3_gi|45383213|ref|NP_989806.1|/1-426, 3_gi|47523074|ref|NP_999302.1|/1-425
Cutoff: 0.2. Archive of all output files
Aligned chains from 1KHX.pdb or together with whole alignment
Selected 40 positions below cutoff (0.2)
Image generated by pymol from SH_1KHX.pdb pdb file with '1-SH' as B-factors and using display.pml pymol script:
DeLano, W.L. The PyMOL Molecular Graphics System (2002) DeLano Scientific, Palo Alto, CA, USA.www.pymol.org
Raw Table
Selected 40 positions below cutoff (0.2)
SH: |
0.00 |
0.04 |
0.08 |
0.12 |
0.16 |
0.20 |
0.36 |
0.52 |
0.68 |
0.84 |
1.00 |
---|
Position |
Entropy |
SH |
Rnk |
Consensus |
---|
Ali |
Ref |
A |
B |
AB |
rel. |
|
|
A |
B |
---|
106 |
Y105 |
0.00 |
0.00 |
1.00 |
1.00 |
0.00 |
4 |
H |
Y |
108 |
W107 |
0.00 |
0.00 |
1.00 |
1.00 |
0.00 |
4 |
F |
W |
207 |
C202 |
0.00 |
0.00 |
1.00 |
1.00 |
0.00 |
4 |
I |
C |
37 |
T37 |
0.32 |
0.00 |
1.17 |
1.00 |
0.00 |
4 |
Li |
T |
105 |
R104 |
0.67 |
0.00 |
1.35 |
1.00 |
0.00 |
4 |
Hq |
R |
104 |
Q103 |
0.79 |
0.00 |
1.40 |
1.00 |
0.00 |
4 |
Yf |
Q |
34 |
P34 |
0.98 |
0.00 |
1.50 |
1.00 |
0.00 |
4 |
Trl |
P |
205 |
V200 |
0.00 |
1.42 |
1.69 |
1.00 |
0.00 |
4 |
N |
IVl |
65 |
V64 |
0.00 |
0.00 |
1.00 |
1.00 |
0.00 |
3 |
I |
V |
63 |
A62 |
0.00 |
0.34 |
1.16 |
1.00 |
0.00 |
3 |
S |
Ae |
47 |
S47 |
0.00 |
0.34 |
1.16 |
1.00 |
0.00 |
3 |
N |
Sa |
49 |
E48 |
0.98 |
0.00 |
1.50 |
1.00 |
0.00 |
3 |
Nsd |
E |
48 |
- |
1.09 |
0.00 |
1.56 |
1.00 |
0.00 |
3 |
Krs |
- |
67 |
M66 |
0.00 |
1.27 |
1.62 |
1.00 |
0.00 |
3 |
N |
LMq |
12 |
F12 |
0.32 |
0.00 |
1.17 |
1.00 |
0.00 |
2 |
Hy |
F |
11 |
A11 |
1.14 |
0.00 |
1.59 |
1.00 |
0.00 |
2 |
Kqls |
A |
6 |
T6 |
1.28 |
0.34 |
1.82 |
1.00 |
0.00 |
2 |
Acen |
Tm |
8 |
S8 |
0.67 |
1.27 |
1.96 |
1.00 |
0.00 |
2 |
Eq |
CSh |
86 |
F85 |
0.00 |
0.00 |
1.00 |
1.00 |
0.00 |
1 |
Y |
F |
100 |
P99 |
0.00 |
0.00 |
1.00 |
1.00 |
0.00 |
1 |
R |
P |
121 |
N120 |
0.00 |
0.00 |
1.00 |
1.00 |
0.00 |
1 |
S |
N |
144 |
Q139 |
0.00 |
0.00 |
1.00 |
1.00 |
0.00 |
1 |
H |
Q |
154 |
R149 |
0.00 |
0.00 |
1.00 |
1.00 |
0.00 |
1 |
K |
R |
171 |
R166 |
0.00 |
0.00 |
1.00 |
1.00 |
0.00 |
1 |
H |
R |
174 |
T169 |
0.00 |
0.00 |
1.00 |
1.00 |
0.00 |
1 |
D |
T |
77 |
R76 |
0.00 |
0.00 |
1.00 |
1.00 |
0.00 |
1 |
H |
R |
81 |
I80 |
0.00 |
0.00 |
1.00 |
1.00 |
0.00 |
1 |
V |
I |
151 |
Q146 |
0.00 |
0.34 |
1.16 |
1.00 |
0.00 |
1 |
E |
Qr |
23 |
Q23 |
0.00 |
0.34 |
1.16 |
1.00 |
0.00 |
1 |
N |
Qt |
184 |
L179 |
0.32 |
0.00 |
1.17 |
1.00 |
0.00 |
1 |
Iv |
L |
136 |
A131 |
0.64 |
0.00 |
1.33 |
1.00 |
0.00 |
1 |
Qeh |
A |
2 |
L2 |
0.98 |
0.34 |
1.67 |
1.00 |
0.00 |
1 |
Vfm |
La |
204 |
S199 |
1.17 |
0.67 |
1.86 |
0.94 |
0.06 |
4 |
Hlr |
Snr |
36 |
L36 |
0.79 |
1.27 |
1.91 |
0.89 |
0.11 |
4 |
Vi |
LMi |
33 |
Q33 |
0.32 |
0.00 |
1.00 |
0.84 |
0.16 |
4 |
Sq |
Q |
187 |
N182 |
0.32 |
0.00 |
1.00 |
0.84 |
0.16 |
1 |
Hn |
N |
118 |
P117 |
0.32 |
0.00 |
1.00 |
0.84 |
0.16 |
1 |
Sp |
P |
206 |
R201 |
0.00 |
0.34 |
0.99 |
0.83 |
0.17 |
4 |
P |
Rp |
94 |
A93 |
0.00 |
0.34 |
0.99 |
0.83 |
0.17 |
1 |
S |
As |
74 |
R73 |
0.00 |
0.34 |
0.99 |
0.83 |
0.17 |
1 |
K |
Rk |