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NatalieQ Results |
The overview table below summarizes the results of the runs. In the edge correctness column the relative number of conserved interactions is shown. The sequence contribution column shows the score of the subordinate objective. This score is defined as the sum of the bit-scores of the aligned node-pairs normalized such that the total sequence contribution is less than the score contribution of one conserved interaction (
). When the results of a run are shown in gray, these results are identical to the previous run. For more information, see the documentation.
Your network format was detected as: edge list.
Overview for Dme from String (topology)
Run Emax Edge correctness Sequence contribution 1 0 1/17 = 0.0588235 0.0091093 2 1e-100 8/17 = 0.470588 0.00794499 3 1e-50 10/17 = 0.588235 0.00845966 4 1e-10 16/17 = 0.941176 0.00890019 5 1 17/17 = 1 0.011376 6 10 17/17 = 1 0.011376 7 100 17/17 = 1 0.011376 Summary of run 3 [E-value cut-off: 1e-50]
Below you find the input and statistics summaries of your run, an interactive network visualization, and tables with the alignment and both conserved and non-conserved query-target interactions. You can download all results as text files for further off-line analysis.
Input
Target network name data/string/dme-7227.string Target network size 13144 nodes and 1996782 edges Query network size 11 nodes and 17 edges Number of matching edges 20 edges E-value cut-off 1e-50 Confidence threshold 10% Statistics
Elapsed time 0.000112057s Edge correctness 10/17 = 0.588235 Sequence contribution 0.00845966 Optimality gap 0% Number of aligned pairs 8 Conserved interactions 10 Non-conserved interactions in query 7 Non-conserved interactions in target 15 Visualization of natalie network alignment
You can translate the drawing by dragging and zoom in and out by using the scroll wheel. If you drag a node, you can change the position of that node. With "Export SVG" you can save an SVG image of the graph for local use.
query target bit score E-value query description target description
NatalieQ query-target interactions
Alignment
Query node Target node E-value Bit score Query description Target description WNT1 7227.FBpp0079060 5e-92 286 (Homo sapiens) (STRING-Protein-Id:9606.ENSP00000293549) 1: dWnt-1. 2: dInt-1. 3: Protein int-1. 4: Protein Wnt-1. 5: Protein wingless. A2MR 7227.FBpp0086821 0 614 (Homo sapiens) (STRING-Protein-Id:9606.ENSP00000243077) 1: Arrow. 2: LP19005p. 3: LDL-related protein LRP6. FZD1 7227.FBpp0075485 5e-177 519 (Homo sapiens) (STRING-Protein-Id:9606.ENSP00000287934) 1: dFz1. 2: Frizzled. 3: Frizzled-1. DVL1 7227.FBpp0073310 2e-143 435 (Homo sapiens) (STRING-Protein-Id:9606.ENSP00000368169) 1: Dishevelled protein. 2: Dishevelled, isoform B. 3: Segment polarity protein dishevelled. GSK3B 7227.FBpp0070454 0 619 (Homo sapiens) (STRING-Protein-Id:9606.ENSP00000324806) 1: SGG. 2: FI05468p. 3: MIP03616p. 4: Shaggy, isoform J. 5: Shaggy, isoform I. 6: Shaggy, isoform M. 7: Shaggy, isoform C. 8: Shaggy, isoform E. 9: Shaggy, isoform L. 10: Shaggy, isoform K. 11: Shaggy, isoform F. 12: Shaggy, isoform H. 13: Protein kinase shaggy. 14: Protein zeste-white 3. APC 7227.FBpp0084720 7e-146 509 (Homo sapiens) (STRING-Protein-Id:9606.ENSP00000257430) 1: APC-like. 2: Adenomatous polyposis coli. CTNNB1 7227.FBpp0089031 0 1059 (Homo sapiens) (STRING-Protein-Id:9606.ENSP00000344456) 1: Armadillo protein. 2: Armadillo segment polarity protein. TLE1 7227.FBpp0089115 0 660 (Homo sapiens) (STRING-Protein-Id:9606.ENSP00000365682) 1: Protein groucho. 2: Enhancer of split m9/10 protein. Conserved interactions
Query node Query node Target node Target node Target confidence WNT1 A2MR 7227.FBpp0079060 7227.FBpp0086821 0.995 WNT1 FZD1 7227.FBpp0079060 7227.FBpp0075485 0.999 A2MR FZD1 7227.FBpp0086821 7227.FBpp0075485 0.975 FZD1 DVL1 7227.FBpp0075485 7227.FBpp0073310 0.999 DVL1 GSK3B 7227.FBpp0073310 7227.FBpp0070454 0.929 DVL1 APC 7227.FBpp0073310 7227.FBpp0084720 0.938 DVL1 CTNNB1 7227.FBpp0073310 7227.FBpp0089031 0.953 GSK3B APC 7227.FBpp0070454 7227.FBpp0084720 0.991 GSK3B CTNNB1 7227.FBpp0070454 7227.FBpp0089031 0.999 APC CTNNB1 7227.FBpp0084720 7227.FBpp0089031 0.99 Interactions in query network but not in target network
Query node Query node Target node Target node DVL1 AXIN1 7227.FBpp0073310 GSK3B AXIN1 7227.FBpp0070454 APC AXIN1 7227.FBpp0084720 CTNNB1 AXIN1 7227.FBpp0089031 CTNNB1 TCF7 7227.FBpp0089031 TLE1 TCF7 7227.FBpp0089115 TCF7 MYC Interactions in target network but not in query network
Target node Target node Target confidence Query node Query node 7227.FBpp0079060 7227.FBpp0073310 0.999 WNT1 DVL1 7227.FBpp0079060 7227.FBpp0070454 0.998 WNT1 GSK3B 7227.FBpp0079060 7227.FBpp0084720 0.742 WNT1 APC 7227.FBpp0079060 7227.FBpp0089031 0.999 WNT1 CTNNB1 7227.FBpp0079060 7227.FBpp0089115 0.299 WNT1 TLE1 7227.FBpp0086821 7227.FBpp0073310 0.997 A2MR DVL1 7227.FBpp0086821 7227.FBpp0070454 0.938 A2MR GSK3B 7227.FBpp0086821 7227.FBpp0084720 0.688 A2MR APC 7227.FBpp0086821 7227.FBpp0089031 0.607 A2MR CTNNB1 7227.FBpp0075485 7227.FBpp0070454 0.989 FZD1 GSK3B 7227.FBpp0075485 7227.FBpp0084720 0.723 FZD1 APC 7227.FBpp0075485 7227.FBpp0089031 0.974 FZD1 CTNNB1 7227.FBpp0075485 7227.FBpp0089115 0.276 FZD1 TLE1 7227.FBpp0070454 7227.FBpp0089115 0.152 GSK3B TLE1 7227.FBpp0089031 7227.FBpp0089115 0.928 CTNNB1 TLE1 Downloads
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